Bailey Laboratory
The Bailey Laboratory focuses on unravelling the molecular pathogenesis of genetic disease and cancers. Through our better understanding of normal biology, we seek to develop novel molecular biomedicine solutions for disease.
About the Bailey Laboratory
The Bailey Laboratory uses multi-disciplinary approaches to understand the complex molecular aetiology of disease. Our molecular, cellular, genetic, biochemical and bioinformatic expertise underpins our research vision.
We functionally characterise tumour suppressor genes and master transcriptional regulators and examine how they are impacted by disease-causing mutations or gene dysregulation. Our ‘multi-omics’ approaches enable us to capture the whole biological landscape of disease pathogenesis.
Furthermore, we are adopting a host-focused approach to improving adeno-associated virus (AAV)-based gene therapies for rare diseases. Our goal is to enable targeted gene therapies to be delivered at a lower dose.
Centre for Rare Diseases & Gene Therapy
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Dr Charles Bailey
Head, Centre for Rare Diseases & Gene Therapy
- Gene Regulation
- Gene Therapy
- Cancer Pathogenesis
- Gene regulation
- Molecular Biology
- Bioinformatics
Orchestrated Intron Retention Regulates Normal Granulocyte Differentiation
Loss-of-function mutations in the glutamate transporter SLC1A1 cause human dicarboxylic aminoaciduria
Iminoglycinuria and hyperglycinuria are discrete human phenotypes resulting from complex mutations in proline and glycine transporters
Structure–function relationships explain CTCF zinc finger mutation phenotypes in cancer
Expression is Essential for Somatic Cell Viability and Protection Against Cancer
People
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Dr Chuck Bailey
Head, Centre for Rare Diseases & Gene Therapy -
Dr Bijay Dhungel
Senior Research Officer
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Dr Mehdi Sharifi Tabar
Research Officer
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Dr Chirag Parsania
Research Officer
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Dr Carl Power
Research Officer
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Cynthia Metierre
Research Officer
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Julie Feng
Senior Research Assistant
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Rajini Nagarajah
Senior Research Assistant
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Joseph Vitale
Research Assistant
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Harrison Bazley
SOMS Honours Student
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Elysha Lui
SOMS Honours Student -
Tinuoye Winjobi
Masters Student -
Atharva Shinde
Masters Student -
Patricia Ascanio
Masters Student -
Dominica Leaver
Biomedical Engineering Student -
Matilda Wynter
Mathew Vadas Award trainee
Student Opportunities
The Bailey Laboratory is committed to developing and training the next generation of early career researchers.
Multidisciplinary projects are currently available for prospective PhD, MPhil, Masters and honours students.
To learn more about current opportunities, please contact Dr Chuck Bailey.
