Bagnall Laboratory

We use high-performance computers to analyse very large sets of genomic data from people with cardiomyopathies, arrhythmia syndromes and sudden cardiac death. By finding new genetic causes of these conditions, we can gain a deeper understanding of the molecular pathways that underlie these disorders. Our computational predictions are validated using the latest laboratory technologies to analyses DNA, RNA and patient-specific cellular models of disease. Research findings from the Bagnall Lab have significantly increased the diagnostic yield in genetic testing for inherited heart diseases, thereby allowing more families to receive the benefits of a precise genetic diagnosis.